Synthesis and structural study of 2-(haloalkyl)-3-methylchromones

ALCÍVAR LEÓN, CHRISTIAN D.; RAMOS GUERRERO, LUIS A.; BONILLA VALLADARES, PABLO M.; ECHEVERRÍA, GUSTAVO A.; PIRO, OSCAR E.; ULIC, SONIA E.; JIOS, JORGE L.; LANGER, PETER

MONATSHEFTE FUR CHEMIE (VIENNA)

SPRINGER WIEN

Año: 2019 vol. 150 p. 1929 - 1940

0026-9247

Abstract: The novel 2-(difluoromethyl)-3-methylchromone, 2-(dichloromethyl)-3-methylchromone, and 3-methyl-2-(perfluoroethyl)chromone were synthesized by a one-pot method and characterized through MS spectrometry, cyclic voltammetry, and vibrational (IR, Raman), UV?Vis, fluorescence, and NMR (1H, 13C, and 19F) spectroscopy. The crystal structure of 2-(difluoromethyl)-3-methylchromone and 2-(dichloromethyl)-3-methylchromone determined by X-ray diffraction methods were used to calculate their intermolecular interactions and crystal lattice energies together with the Hirshfeld surface analysis. Graphic abstract: [Figure not available: see fulltext.].