INVESTIGADORES
ECHEVERRIA Gustavo Alberto
artículos
Título:
Synthesis, Physicochemical and Biological Studies of a ternary Co(II) complex with Sulfaquinoxaline and 2,2?-Bipyrimidine as ligands
Autor/es:
CRISTIAN VILLA-PÉREZ; J. F. CADAVID-VARGAS; G.E. CAMÍ; F. GIANNINI; M.E. CHACÓN VILLALBA; G.A. ECHEVERRIA; I.C. ORTEGA; G.C. VALENCIA; S.B. ETCHEVERRY; D.B. SORIA
Revista:
INORGANICA CHIMICA ACTA
Editorial:
ELSEVIER SCIENCE SA
Referencias:
Lugar: Amsterdam; Año: 2016 vol. 447 p. 127 - 133
ISSN:
0020-1693
Resumen:
A novel ternary complex ofCobalt(II) with 4-Amino-N-2-quinoxalinylbenzenesulfonamide(sulfaquinoxaline, SQO), and 2,2?-bipyrimidine (Bpym) as ligands has beenprepared. The complex has been characterized based on elemental analyses, FTIRand Raman spectroscopy. Its structure, [Co(SQO)2(Bpym)] was determinedby X-ray diffraction methods. It crystallizes in the triclinic P-1 space groupwith a=10.5381(2), b=13.6469(2), c=13.8409(3) Å, a=95.058(2), β= 93.769(2), γ=93.750(2)° and Z=2 molecules per unitcell. Thermogravimetric (TG) and Differential thermal analysis (DT) were alsostudied.The aquatic toxicity of the complex was evaluatedon the two following test organisms: Danio rerio (cebritas) y Cyprinuscarpio haematopterus (carpas koi). Antibacterial activity was screenedagainst Escherichia coli (ATCC 8739), Salmonella typhimurium (ATCC14028), Staphylococcus aureus (ATCC 49775) and Bacillus cereus (ATCC10987). The antiproliferative effect ofthe tested complex [Co(SQO)2(Bpym)] in the human osteoblast (MG-63) cell line wasalso studied.
