INVESTIGADORES
GRASSELLI Mariano
artículos
Título:
Preparation of Functional Currant-Bun-like Fumed Silica/polymethacrylate Nanoparticles by Radiation-Induced Polymerization
Autor/es:
LEANDRO J MARTINEZ; MIRNA LORENA SANCHEZ; KIKOT, PAMELA; ROBERTO CANDAL; MARIANO GRASSELLI
Revista:
COLLOIDS AND SURFACES B-BIOINTERFACES
Editorial:
ELSEVIER SCIENCE BV
Referencias:
Lugar: Amsterdam; Año: 2014 vol. 463 p. 110 - 117
ISSN:
0927-7765
Resumen:
Fumed silica (FS) is one of the few nanomaterials used in large scale in the production of several industrial products. In addition, the very low toxicity of these nano-sized particles led them to become excellent raw materials to develop novel applications in the field of downstream processing of bioproducts. In this work, we prepared and characterized a colloidal composite based on fumed silica with protein adsorption properties. This nanocomposite was prepared by radiation-induced polymerization of glycidyl methacrylate (GMA) dissolved in an aqueous suspension of FS without stirring. According to the initial GMA/FS ratio, mono-disperse nanoparticles from 60 to 195 nm were obtained. Sulfonic nanoparticles allowed reversible lysozyme adsorption up to 270 mg/g. The nanomaterials prepared have potential application as protein-capture materials in the field of downstream processing of proteins.
