INVESTIGADORES
PICOLLO Maria Ines
congresos y reuniones científicas
Título:
Synergized pediculicide lotions for the control of permethrin resistant head lice (Phthiraptera: Pediculicidae)
Autor/es:
VASSENA C; TOLOZA A; MOUGABURE G; PICOLLO M I
Lugar:
Park City, Utah
Reunión:
Congreso; 5º International Conference on Phthiraptera 2014; 2014
Institución organizadora:
University of Utah
Resumen:
Infestation
caused by Pediculus humanus capitís is one of the most important
infestations that occur worldwide and infest millions of children and adults
every year, especially after the detection of head lice strains that are
resistant to the insecticides available in the market.
In
Argentina, field populations of the head louse have developed resistance to permethrin
and other pyrethroids. The resistance in P.
h. capítís is a phenomenon of great concern because of the lack of novel
insecticides introduced into the market as new safe products for chemical
control of head lice.
The aim of this work was the development of a lotion
containing ivermectin and an alcohol coadjuvant to improve biological effect.
We
investigated the adulticidal and ovicidal activity of Ivermectin and spinosad
and experimental lotions based on this insecticide against permethrin-resistant
head lice.
We test different combination of actives with
different aliphatic alcohols as synergists.
The
effectiveness of experimental lotions was evaluated by the immersion method.
The
Lethal Concentration 50% showed that the lotions with ivermectin and spinosad are
more effective than those with permethrin on adults but ivermectin was better
than spinosad on nits.
The
modification of pediculicidal formulations to enhance insecticide activity has
shown to be one good strategy to optimize the effectiveness of the available
products indicating that are a good alternative for commercial head lice
products.