INVESTIGADORES
RODRIGUEZ Juan Bautista
artículos
Título:
Enantioselective Synthesis of (+)-Neplanocin F.
Autor/es:
COMIN, MARÍA JULIETA; LEITOFUTER, JULIETA; RODRIGUEZ, JUAN BAUTISTA
Revista:
TETRAHEDRON
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Año: 2002 vol. 58 p. 3129 - 3136
ISSN:
0040-4020
Resumen:
(+)-Neplanocin F ((+)-5), a minor component of the neplanocin family of antibiotics was enantioselectively synthesized starting from D-ribono-1,4-lactone via a convergent approach in fourteen steps. This synthetic approach employed a regioselective protection of a secondary allylic hydroxyl group over a homoallylic one as key step