INVESTIGADORES
RODRIGUEZ Juan Bautista
artículos
Título:
Synthesis of C-5'-nor-Dideoxycarbanucleosides Structurally Related to Neplanocin C
Autor/es:
COMIN, MARÍA JULIETA; PUJOL, CARLOS A.; DAMONTE, ELSA B.; RODRIGUEZ, JUAN BAUTISTA
Revista:
NUCLEOSIDES & NUCLEOTIDES
Editorial:
Marcel Dekker, Inc.
Referencias:
Año: 1999 vol. 18 p. 2219 - 2231
ISSN:
0732-8311
Resumen:
Purine carbanucleosides built on a 6-oxabicyclo[3.1.0]hexane template were synthesized from readily available 2-cyclopentenone employing a Mitsunobu reaction to incorporate the base onto the carbocyclic ring. Both adenosine and guanosine analogues exhibited moderate antiviral activity.
