INVESTIGADORES
RODRIGUEZ Juan Bautista
artículos
Título:
Synthesis and Biological Activity of Synthetic Juvenile Hormone Analogues for Trypanosoma cruzi.
Autor/es:
RODRIGUEZ, JUAN BAUTISTA; GROS, EDUARDO GERVASIO; STOKA, ANGEL M.
Revista:
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Año: 1991 vol. 1 p. 679 - 682
ISSN:
0960-894X
Resumen:
Several derivatives of geraniol, geranylacetone, and farnesol bearing carbonate
and thiolcarbonate functional groups as well as several derivatives of 4-phenoxyphenol
were synthesized and tested for their respective biological activity as growth inhibitors
for Trypanosoma cruzi, and for inhibition of tritium-labelled thymidine incorporation in
T. cruzi cells. The results indicated that some JHA showed important activity against the
development of the cells.Trypanosoma cruzi, and for inhibition of tritium-labelled thymidine incorporation in
T. cruzi cells. The results indicated that some JHA showed important activity against the
development of the cells.
