INVESTIGADORES
RODRIGUEZ Juan Bautista
artículos
Título:
Biological Evaluation of Two Potent Inhibitors of Trypanosoma cruzi epimastigotes against the Intracellular Form of the Parasite
Autor/es:
RODRIGUEZ, JUAN BAUTISTA; ZHONG, LI; DOCAMPO, ROBERTO; GROS, EDUARDO GERVASIO
Revista:
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Año: 1996 vol. 6 p. 2783 - 2786
ISSN:
0960-894X
Resumen:
S-Ethyl-[3,7,11-trimethyl-10,11-epoxy-2E,6E-dien-1-yl-] (1) and 4-phenoxyphenoxy ethyl tetrahydropyranyl ether (2) were shown to be very active antireplicative agets against intracellular Trypanosoma cruzi amastigotes in in vitro assays. Both of them had previuosly presented high biological activity as growth inhibitors of the epimastigote form of the parasite.
