INVESTIGADORES
RODRIGUEZ Juan Bautista
artículos
Título:
Growth Inhibitory Effect of Juvenile Hormone Analogues on Epimastigotes of Trypanosoma cruzi.
Autor/es:
RODRIGUEZ, JUAN BAUTISTA; ZHONG, LI; DOCAMPO, ROBERTO; WIMMER, ZDNEK; GROS, EDUARDO GERVASIO
Revista:
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Año: 1998 vol. 8 p. 3257 - 3260
ISSN:
0960-894X
Resumen:
Several compounds, structurally related to the insect growth regulator Fenoxycarb, exhibited interesting inhibition action to control proliferation of Trypanosoma cruzi, the parasite responsible for Chagas disease. Some of these drugs were shown to be potent growth inhibitors of this parasite. All of these drugs had previously presented juvenoid activity on several non-related bug species such as Tenebrio molitor, Galleria mellonella, Dysdercus cingulatos, and Pyrrhocoris apterus.
