INVESTIGADORES
MATA Ernesto Gabino
artículos
Título:
Synthesis of multicyclic â-lactam derivatives via solid phase-generated ketenes
Autor/es:
MENDEZ, L.; MATA, E.G.
Revista:
J. Comb. Chem.
Editorial:
AMER CHEMICAL SOC
Referencias:
Lugar: Washington; Año: 2010 vol. 12 p. 810 - 813
ISSN:
1520-4766
Resumen:
An efficient approach for the solid-phase synthesis of multicyclic â-lactam derivatives is described. The key step is the cycloaddition reaction between an immobilized ketene and different cyclic imines to afford the corresponding benzofused carbacepham derivatives in high yield for the overall synthetic sequence