Quinolones for veterinary use, quantification chemometrically assisted in edible animal tissues by excitation–emission fluorescence–kinetic data obtained through Fenton degradation

M.B. ANZARDI; G.A. IBAÑEZ; J.A. ARANCIBIA

JOURNAL OF FOOD COMPOSITION AND ANALYSIS

ACADEMIC PRESS INC ELSEVIER SCIENCE

Lugar: Amsterdam; Año: 2022 vol. 113 p. 104707 - 104707

0889-1575

Four quinolones (marbofloxacin, sarafloxacin, danofloxacin and enrofloxacin) were simultaneously quantified inedible animal tissues. A strategy based on third–order data, excitation–emission matrices as function of the timereaction during their Fenton degradation were employed to build a four–way calibration model. Unfoldingpartial least–squares (U–PLS) coupled to trilinearization residual (RTL) was the algorithm of choice to overcomeboth the high spectral overlapping among the analytes, and also the background signal present in the complexmatrices. Bovine liver and porcine meat tissues were fortified with the analytes under study at different concentrationlevels, considering the maxima residual levels (MRLs) established by European Community. A recoverytest was performed attaining recovery values ranging from 86 % to 123 % for all the analytes. Inaccordance with the principles of Green Analytical Chemistry, the proposed methodology enables the determinationof the quinolones in complex matrices involving a simple extraction/clean–up procedure, a short time ofanalysis, and a no sophisticated instrumental.