Adrenal function at different stages of chronic renal disease

ARREGGER AL, CARDOSO EML, DORADO E, ZUCCHINI A, SANCHEZ R, CONTRERAS LN.

Houston

Congreso; 94th Annual Meeting of the Endocrine Society; 2012

Endocrine Society

Excess or deficiency of corticoadrenal steroid secretion affects quality of life and is associated to early mortality in general population. Multiple endocrine disturbances are seen in patients with end- stage renal disease and it diagnosis is a challenge due to pitfalls in biochemical testing interpretation. This study aims to validate the accuracy of first line tests used to rule out adrenal disfunction in patients with chronic kidney disease in stages (S) 1 to 4 (K/DOQI CDK). We screened 34 adults ( 13 has primary kidney disease, 14 had hypertension, 3 had diabetes mellitus type 2, and 4 had obesity). Coclusion: patients in S1 did not show false positive results. At difference variable data were obtained in S2 to S4. In these stages further and costs consuming tests were required to rule out adrenal dysfunction.