ENCAPSULATION OF NATURAL ANTIOXIDANTS OF POTATO (Ipomea Batata) IN BIODEGRADABLE NANOPARTICLES OF POLYLACTIC ACID

NORMA DACCORSO; BEATRIZ GUERRERO; NANCY LIS GARCIA; GRACIELA CORBINO

Virginia

Conferencia; 21st Annual Green Chemistry & Engineering Conference | June 13-15, 2017 | Reston, Virginia; 2017

The encapsulation of active ingredients in colloidal nanovehicles (nanocarriers) has an interesting potential to be used in controlled release. There is a great interest of different industries in the encapsulation of active ingredients in various types of nanoparticles (NPs), thanks to their particular properties of improving the stability and solubility in water of the type of compounds to be encapsulated.The objective of this research is the elaboration, characterization and optimization of polylactic acid (PLA) nanoparticles and a study on the encapsulation efficiency (EE) of antioxidants from a potato peel extract. There are two important points: Low molecular weight PLA has been efficiently and economically synthesized in the laboratory and nanoparticles have been efficiently obtained. The second point is that the antioxidant used is obtained from the waste of the potato skin, that is to say a very cheap source of production.The NPs of PLA were elaborated by means of the technique emulsion - evaporation of solvent. The results demonstrated that this technique is satisfactory for the system: antioxidant extract - PLA and there are no major losses or degradation of antioxidants during this process.The nanoparticles were evaluated by Dynamic Light Scattering (DLS) and Scanning Electron Microscopy (SEM) and showed satisfactory narrow size distributions. The encapsulation efficiency reaching even 98%. The nanoparticles were finally well dispersed in a PLA film. SEM observations show a good dispersion of the nanoparticles throughout the structure of the film, demonstrated that they can be applied intelligently in films for future purposes.