Clicking sugars onto sugars: oligosaccharide analogues and glycoclusters on carbohydrate scaffolds

MARÍA LAURA UHRIG; JOSÉ KOVENSKY

Click Chemistry in Glycoscience

John Wiley & Sons

Lugar: Nueva York; Año: 2012;

We review herein the recent applications of the copper(I) catalyzed azide-alkyne cycloaddition to couple carbohydrates and produce compounds of various architectures, molecula weights and biological properties. The different parts of the chapter correspond to the nature of the products, limited to the examples where carbohydrates are connected by triazol linkers: oligosaccharide analogues, cyclodextrins carrying clicked sugars, macrocyclic analogues and multivalen glycoclusters on carbohydrate scaffolds.