Pushing the photodelivery of nitric oxide to the visible: Are {FeNO}7 complexes good candidates?

SLEP, LEONARDO D.; PERDOMÉNICO, JULIÁN; WEYHERMÜLLER, THOMAS; WEYHERMÜLLER, THOMAS; LEVIN, NATALIA; BILL, ECKHARD; LEVIN, NATALIA; BILL, ECKHARD; SLEP, LEONARDO D.; PERDOMÉNICO, JULIÁN

DALTON TRANSACTIONS

ROYAL SOC CHEMISTRY

Año: 2017 vol. 46 p. 16058 - 16064

1477-9226

Photodelivery of NO requires stable compounds which can be made reactive by irradiation with (visible) light. Traditional {MNO}6 complexes require a substantial ligand design to shift their absorption spectra to the appropriate region of the electromagnetic spectrum. [Fe((CH2Py2)2Me[9]aneN3)(NO)](BF4)2 is a new {FeNO}7 octahedral coordination compound, which is thermally and air-stable in solution. Illumination with a 450 nm light source induces significant photodetachment of the coordinated NO (NO = 0.52 mol einstein-1), suggesting that {FeNO}7 compounds can be in fact suitable compounds for therapeutic NO-photorelease.