Spontaneous Ca++ activity and long-term memory rectativation in a mushroom body like-structure centre of the crab Neohelice

FRANCISCO JAVIER MAZA; . LUIS DANIEL SUÁREZ1; PEDRO CAFFARO, KARINA A. BARREIRO MARIANO G. BLAKE Y ALEJANDRO DELORENZI; FRANCISCO JAVIER MAZA

CABA

Congreso; Sociedad Argentina de Neurociencias; 2020

Sociedad Argentina de Neurociencias

A wide range of neuronal oscillations has been described in high-order brain centers of bilateral animals. The proposed roles of such rhythmic activities include modulation of input selection and plasticity, linking the activity of different neuronal assemblies, and integration and consolidation of information. Evidence suggests monoamines may control the oscillatory activity that reflects the internal states of the organism. In the high-order memory centers of insects, the mushroom bodies, projections of dopaminergic neurons present slow oscillating activity necessary to memory consolidation. Structural and physiological studies suggest a correspondence between crustacean hemiellipsoid bodies and insect mushroom bodies. In N. granulata, the hemiellipsoid body shows, for instance, aminergic innervation, elevated expression of proteins necessary for memory processes, and plasticity in neuronal activity that reflects context‐dependent memory attributes. Preliminary data analysis shows, utilizing in vivo calcium imaging, spontaneous low-frequency activity in both naïve and in animals trained in an aversive memory paradigm 24 h before. In trained animals, the activity evoked upon the presentation of the aversive stimulus differs for naïve crabs. Data provide ground to our next steps exploring the roles of high-order brain center oscillating activity, including changes in animal´s internal states, stimuli processing, and memory reactivation/expression processes