Porphyria Cutanea Tarda in Argentinean Young Women. Main Triggering Factors.

BATLLE ALCIRA; MELITO, VIVIANA; PARERA, VICTORIA; ROSSETTI, MARIA VICTORIA

Burdeos

Congreso; ICPP Porphyrins and Porphyrias 2017; 2017

Porphyria Cutanea Tarda (PCT), represents about 70% of patients with Porphyria. Up to 2016, including Type I and Type II PCT, we diagnosed 2048 patients with overt PCT. This disease, mainly triggered by hepatotoxic drugs and hepatothropic virus, usually appears in adult life, over 40 years old, excluding Type II patients and subjects with human B and C virus infections (HBV, HCV) or human immunodeficiency virus (HIV). In the present work we have analyzed the precipitating agents in 80 women, negative for HBV, HCV or HIV infection, who developed PCT before they were 40 years old. This group represents almost 20% of total women with PCT (422). Mean age of manifestation was significantly lower (29.0±6.4, p