CONICET | Buscador de Institutos y Recursos Humanos

Resveratrol, a natural polyphenolic stilbenoid widely found ingrapes and wines, displays beneficial properties such as cardioprotective,antioxidant and anti-inflammatory activities. Transresveratrol(RSV) is the most bioactive and more abundantstereoisomer found in nature. Despite the positive properties ofRSV, there are various factors that limit its effectiveness,including low aqueous solubility, low oral bioavailability andchemical instability. During the last years, an increasing numberof strategies such as nano and micro encapsulation have beendeveloped in order to overcome these limitations and enhancethe use of RSV in nutritional and pharmaceutical applications.This Review summarizes the advances and main properties ofseveral RSV carriers and delivery systems reported during thelast 5 years.