Facilitated proton transfer across liquid|liquid interfaces under forced hydrodynamic conditions. Determination of partition coefficient of neutral weak bases.

F. VEGA MERCADO, J.M. OVEJERO, F.M. ZANOTTO, R. SERIAL, M.I. VELASCO, R.A. FERNÁNDEZ, R.H. ACOSTA, S.A. DASSIE

JOURNAL OF ELECTROANALYTICAL CHEMISTRY

ELSEVIER

Lugar: Amsterdam; Año: 2017 vol. 791 p. 64 - 74

0022-0728

A novel quantitative methodology to determine the partition coefficients of neutralweak bases is developed. Thisnew electrochemical approach is based on the measurement of the total transferred charge across the oil|waterinterface under forced hydrodynamic conditions. The complete procedure has been validated by computationalsimulations and experimental results (Tylosin A). In addition, flow pattern caused inside the electrochemical cellwas simulated with computational fluid dynamics using finite element methods and correlated with experimentalresults obtained by magnetic resonance imaging.