-“Synthesis of three polymeric macroporous rods systems: study of reaction parameters over the porous properties”

RUBEN DARIO ARRUA; JULIO SAN ROMAN; ALBERTO GALLARDO; MIRIAM STRUMIA; CECILIA I. ALVAREZ IGARZABAL

MATERIALS CHEMISTRY AND PHYSICS

Elsevier

Año: 2008 vol. 112 p. 1055 - 1060

0254-0584

Polymeric macroporous rod systemswere prepared using N-acryloyl-tris(hydroxymethyl)aminomethane (NAT) and glycidyl methacrylate (GMA) as mono-vinyl monomers and N,N-methylenebisacrylamide (BIS) or trimethylolpropane trimethacrylate (TRIM) as crosslinking agents. The reactions were performed in the presence of a ternary porogenic diluent (composed by dimethylsulfoxide, tetradecanol and poly(ethylenglycol) 6000 (PEG 6000)) and azobisisobutyronitrile (AIBN) as initiator, by freeradical crosslinking copolymerization. The effect of polymerization temperature, porogenic mixture and crosslinker was analyzed. The results showed that a lower polymerization temperature and an increase in the amount of non-solvating diluents (tetradecanol and PEG 6000) in the reaction mixture led to products with higher porosity. The prepared monolithswere promising as potential base supports for different chromatography processes, especially those synthesized with GMA, since its incorporation allows to bind different ligands in a direct coupling reaction. (BIS) or trimethylolpropane trimethacrylate (TRIM) as crosslinking agents. The reactions were performed in the presence of a ternary porogenic diluent (composed by dimethylsulfoxide, tetradecanol and poly(ethylenglycol) 6000 (PEG 6000)) and azobisisobutyronitrile (AIBN) as initiator, by freeradical crosslinking copolymerization. The effect of polymerization temperature, porogenic mixture and crosslinker was analyzed. The results showed that a lower polymerization temperature and an increase in the amount of non-solvating diluents (tetradecanol and PEG 6000) in the reaction mixture led to products with higher porosity. The prepared monolithswere promising as potential base supports for different chromatography processes, especially those synthesized with GMA, since its incorporation allows to bind different ligands in a direct coupling reaction. (NAT) and glycidyl methacrylate (GMA) as mono-vinyl monomers and N,N-methylenebisacrylamide (BIS) or trimethylolpropane trimethacrylate (TRIM) as crosslinking agents. The reactions were performed in the presence of a ternary porogenic diluent (composed by dimethylsulfoxide, tetradecanol and poly(ethylenglycol) 6000 (PEG 6000)) and azobisisobutyronitrile (AIBN) as initiator, by freeradical crosslinking copolymerization. The effect of polymerization temperature, porogenic mixture and crosslinker was analyzed. The results showed that a lower polymerization temperature and an increase in the amount of non-solvating diluents (tetradecanol and PEG 6000) in the reaction mixture led to products with higher porosity. The prepared monolithswere promising as potential base supports for different chromatography processes, especially those synthesized with GMA, since its incorporation allows to bind different ligands in a direct coupling reaction. (BIS) or trimethylolpropane trimethacrylate (TRIM) as crosslinking agents. The reactions were performed in the presence of a ternary porogenic diluent (composed by dimethylsulfoxide, tetradecanol and poly(ethylenglycol) 6000 (PEG 6000)) and azobisisobutyronitrile (AIBN) as initiator, by freeradical crosslinking copolymerization. The effect of polymerization temperature, porogenic mixture and crosslinker was analyzed. The results showed that a lower polymerization temperature and an increase in the amount of non-solvating diluents (tetradecanol and PEG 6000) in the reaction mixture led to products with higher porosity. The prepared monolithswere promising as potential base supports for different chromatography processes, especially those synthesized with GMA, since its incorporation allows to bind different ligands in a direct coupling reaction. N-acryloyl-tris(hydroxymethyl)aminomethane (NAT) and glycidyl methacrylate (GMA) as mono-vinyl monomers and N,N-methylenebisacrylamide (BIS) or trimethylolpropane trimethacrylate (TRIM) as crosslinking agents. The reactions were performed in the presence of a ternary porogenic diluent (composed by dimethylsulfoxide, tetradecanol and poly(ethylenglycol) 6000 (PEG 6000)) and azobisisobutyronitrile (AIBN) as initiator, by freeradical crosslinking copolymerization. The effect of polymerization temperature, porogenic mixture and crosslinker was analyzed. The results showed that a lower polymerization temperature and an increase in the amount of non-solvating diluents (tetradecanol and PEG 6000) in the reaction mixture led to products with higher porosity. The prepared monolithswere promising as potential base supports for different chromatography processes, especially those synthesized with GMA, since its incorporation allows to bind different ligands in a direct coupling reaction. (BIS) or trimethylolpropane trimethacrylate (TRIM) as crosslinking agents. The reactions were performed in the presence of a ternary porogenic diluent (composed by dimethylsulfoxide, tetradecanol and poly(ethylenglycol) 6000 (PEG 6000)) and azobisisobutyronitrile (AIBN) as initiator, by freeradical crosslinking copolymerization. The effect of polymerization temperature, porogenic mixture and crosslinker was analyzed. The results showed that a lower polymerization temperature and an increase in the amount of non-solvating diluents (tetradecanol and PEG 6000) in the reaction mixture led to products with higher porosity. The prepared monolithswere promising as potential base supports for different chromatography processes, especially those synthesized with GMA, since its incorporation allows to bind different ligands in a direct coupling reaction. N,N-methylenebisacrylamide (BIS) or trimethylolpropane trimethacrylate (TRIM) as crosslinking agents. The reactions were performed in the presence of a ternary porogenic diluent (composed by dimethylsulfoxide, tetradecanol and poly(ethylenglycol) 6000 (PEG 6000)) and azobisisobutyronitrile (AIBN) as initiator, by freeradical crosslinking copolymerization. The effect of polymerization temperature, porogenic mixture and crosslinker was analyzed. The results showed that a lower polymerization temperature and an increase in the amount of non-solvating diluents (tetradecanol and PEG 6000) in the reaction mixture led to products with higher porosity. The prepared monolithswere promising as potential base supports for different chromatography processes, especially those synthesized with GMA, since its incorporation allows to bind different ligands in a direct coupling reaction.