INSIBIO   05451
INSTITUTO SUPERIOR DE INVESTIGACIONES BIOLOGICAS
Unidad Ejecutora - UE
artículos
Título:
Is the lysis of the ovarian follicles of amphibian an indicator or endocrine disruption?. A statistical approach
Autor/es:
ZELARAYÁN LI; MATAS E; BENZAL G; ADERA MN
Revista:
BIOCELL
Editorial:
Biocell
Referencias:
Año: 2019 vol. 43 p. 81 - 81
Resumen:
Amphibians develop in aquatic environments and can be considered biological indicators of environmental degradation caused by endocrine disruptors (ED). Among ED effects, defective development of oocytes and interference in their hormonal signaling processes have been reported. In this study we statistically analyzed the maturation of the ovarian follicles of Rhinella arenarum and their lysis during the last three decades as possible indicators of the effects of ED. The experimental data obtained from ovarian follicles of R. arenarum, treated in vitro with Ringer´s solution (RM) and progesterone (P4) (10-6 M), were subjected to statistical analysis by means of the Chi-square test for comparison of proportions, to Marascuilo procedure to determine differences between decades and to the T-test for paired data. A level of significance of 0.05 was set. The chi-square test indicates that the lysis of R. arenarum follicles increased significantly (p