Bioactivity of semisynthetic eugenol derivatives against Spodoptera frugiperda (Lepidoptera: Noctuidae) larvae infesting maize in Colombia

VARGAS-MÉNDEZ, LEONOR Y.; MERCHAN-ARENAS, DIEGO R.; SANABRIA-FLÓREZ, PEDRO L.; KOUZNETSOV, VLADIMIR V.; SAAVEDRA-REYES, LAURA M.

Saudi Journal of Biological Sciences

Elsevier B.V.

Año: 2018

1319-562X

The anti-acetylcholinesterase, larvicidal, antifeedant activities and general toxicity of 15 semisynthetic eugenol derivatives based on clove oil (including the own oil), were evaluated against the maize armyworm, Spodoptera frugiperda (J.E. Smith). Therefore, promising eugenol molecules were classified with larvicidal, anti-acetylcholinesterase and antifeedant activities for controlling this pest. During structure?activity relationship studies and physicochemical profile analysis, it was found that among tested molecules 1?15, eugenol 1, prenyl eugenol 4, isoeugenol 8 and isoeugenol acetate 11 exhibited lethal effects LD50 at concentrations