The prospect of metal-catalyzed C-C forming cross coupling reactions in modern solid phase organic synthesis

TESTERO, S. A.; MATA, E. G.

J. Comb. Chem.

ACS

Lugar: Washington; Año: 2008

1520-4766

In conclusion, although many challenges have been overcome, the research in metal-catalyzed chemistry will continue in the future, giving rise to new reaction and novel and more efficient catalysts. Therefore, new and very interesting chemistry will be amenable for translating to solid-phase, which will certainly improve the existing methodologies. Innovative technologies such as microwave and nanoparticles, will also contribute to such improvement. Definitely, very stimulating developments can be anticipated in the area of metal catalyzed C-C forming cross reactions in solid phase and their application to the generation of libraries of complex pharmaceutically important molecules.