Chemical and green synthesis of silver nanoparticles and its antifungal activity against

J. E. MUSSIN; E. SANMARTIN-MARTINEZ; G. GIUSIANO; M.V. ROLDAN; M.A. SOSA; F. ROJAS ; N. PELLEGRI

Amsterdam

Congreso; 20th Congress of the International Society for Human and Animal Mycology,30 Juio al 4 Julio 2018; 2018

International Society for Human and Animal Mycology

Objective: Nanotechnology is an important field of the modern research dealing with synthesis and manipulation of thestructure of matter ranging from approximately 1 to 100 nm in size, commonly called nanomaterials. Nanoparticles can be preparedthrough a variety of physical and chemical processes which are costly and affect the environment. Phytonanotechnology emerges as amethod of green synthesis in which plants are used for the synthesis of nanoparticles, as a technology that respects the environment.The noble metal nanoparticles show unique and considerably different physical and chemical properties compared to their macroscaled counterparts. Silver is one of the noble metals with antimicrobial activity and lower toxicity for animal cells. Due to theirpotential application in human and animal medicine for treating skins fungal infections, interest in silver nanoparticles (AgNP) havebeen increased in the last years. Yeasts of Malassezia genus are considered etiological agent of pityriasis versicolor and Malasseziafolliculitis, associated agents in seborrheic dermatitis/dandruff and a contributory factors to exacerbate other skin disorders.Objectives of this work were to obtain AgNP by chemical and green synthesis and to study its in vitro antifungal activityagainst clinical isolates of Malassezia furfur