Molecular basis of clinical metabolomics.

DIEGO FABIAN GOMEZ CASATI; BUSI, MARIA VICTORIA

Clinical Molecular Medicine: Principles and Practice.

Elsevier

Lugar: Londres; Año: 2020; p. 47 - 55

Metabolomics, the comprehensive high-throughput analysis in which all the metabolites in a biological system are identified and quantified [1,2], has emerged as a functional genomics methodology which helps to better understand the complex molecular interactions in biological systems [3]. Metabolomics strategies are closelyrelated to other omics, such as genomics, transcriptomics, and proteomics, because it represents the logical progression from large-scale analysis of nucleic acids and proteins at the systems level [4,5]. Recently, metabolomics became essential as a tool in medicine, with an important role in the diagnosis and prevention of numerous diseases and in the design of strategies to carry out an adequate treatment for each pathological condition [6].