PPP Family of Serine/Threonine Protein Phosphatases Key Players in Plant Development and Adaptive Responses

MUÑIZ GARCÍA, MARÍA NOELIA; CAPIATI DANIELA ANDREA; CORTELEZZI JUAN IGNACIO; GROBLY IARA MARLENE; MUÑIZ GARCÍA, MARÍA NOELIA; CAPIATI DANIELA ANDREA; CORTELEZZI JUAN IGNACIO; GROBLY IARA MARLENE

Advances in Medicine and Biology

Nova Science Publishers

Año: 2020; p. 179 - 203

Reversible protein phosphorylationis a major form of post-traslational modification that regulates many vellular processes. Although there are few plant protein phosphatases in comparison with their protein kinase partners, their function is as relevant as that of protein kinases. Many serine/threonine (ser/thr) protein phosphatases have been identified in plants: PP1, PP2A, PP2C, PP4, PP5, PP6, PP7, protein phosphatases with kelch-repeat domains and bacterial-like protein phosphatases. Over the last three decades of research, the cellular functions of plant ser/thr phosphatases have been documented, and specific roles for these enzymes have been characterized with increasing detail. The functional characterization has been accompanied by structural and biochemical data, leading to major advances in the understanding of their molecular mechanism of action.