Differential roles for polyamines in the oxidative stress response of Pseudomonas syringae

LEANDRO SOLMI; FRANCO RUBEN ROSSI; MATIAS FERNANDO ROMERO; OSCAR RUIZ; MARCEL BACH-PAGES; GAIL M. PRESTON; ANDRÉS GÁRRIZ

Southampton

Simposio; Young Microbiologists Symposium; 2020

University of Southampton

Putrescine (Put) and spermidine (Spd) are the main polyamines (PAs) found in bacteria (1). These compounds comprehend a family of small aliphatic molecules implicated in protein synthesis and regulation, DNA integrity and stress resistance (2). The contribution ofPAs to oxidative stress tolerance in human pathogens such as Escherichia coli and Pseudomonas aeruginosa has been clearly documented (3, 4, 5), but their functions in the stress response activated in other types of bacteria have been poorly explored. In this study, we unveiled an important role for PA homeostasis during the oxidative stress response in the phytopathogenic bacteria Pseudomonas syringae pv. tomato DC3000.