Differential selection patterns between sexes could be revealed by ROH analysis in dairy goats

DEMYRA-PEYRAS SEBASTIAN; PIROSANTO YAMILA; RAMON MANUEL; ZIEGLER TATIANA; SANCHEZ MANUEL ; FERNANDEZ MARIA ELENA ; MUÑOZ EVA; SOLE MARINA; MOLINA ANTONIO

Lleida

Congreso; 37th International Society for Animal Genetics Conference; 2019

International Society for Animal Genetics

Differential selection patterns between sexes could be revealed by ROH analysis in dairy goats S Demyda-Peyrás*1,2; Yamila Pirosanto1,2; Manuel Ramon#; Tatiana Ziegler1,2; Manuel Sanchez; Maria Elena Fernandez1,2; Eva Muñoz; Marina Solé and Antonio Molina. 1Instituto de Genética Veterinaria , La Plata, Buenos Aires, Argentina, 2Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, La Plata, Buenos Aires, Argentina, 3Department of Animal Breeding and Genetics Swedish University of Agricultural Sciences , Uppsala, Sweden, 4Departamento de Medicina y Cirugía Animal, Universidad de Córdoba, Córdoba, España, 5University of California, Davis, Davis, CA, USA, #CERSYRA-IRIAF, Valdepeñas, España Runs of homozygosity (ROH) are becoming a valuable tool to analyze the evolution and genomic characteristics in animal populations. In goats, they were recently employed to determine the history of the domestication and adaptation processes of more than 100 breeds. In this study, we determined ROH patterns of 624 goats belonging to the Spanish Florida breed selected by low average relatedness in order to determine sex-related differences. Average ROH length, count and FROH (as a measure of the proportion of the genome covered by ROH) were obtained per individual, chromosome and sex group using DETECTRUNS package of R software. Statistical differences were determined using general linear models (GLM and LS preplanned comparison test). Our results showed that males have longest ROH than females (2559896 vs 2472068 bb respectively, P