ESSENTIAL OIL COMPOSITION AND ANTIBACTERIAL ACTIVITY OF WILD POPULATIONS OF ARTEMISIA MENDOZANA (ASTERACEAE)

LIMA BEATRIZ; LÓPEZ SB; HADDAD M; ZYGADLO JA; FERESIN G; CABALLERO D; TAPIA A; E SUERO.

Potrero de los Funes

Congreso; XXIX Reunión Científica Anual de la Sociedad de Biología de Cuyo; 2012

Sociedad de Biología de Cuyo

Most of the antimicrobial activity in EOs is found in its compounds oxygenated terpenoids (e.g., alcohols and phenolic terpenes), while some components hydrocarbons also exhibit antimicrobial effects. Some studies have demonstrated that whole EOs usually have higher antibacterial activity than the mixtures of their major components, suggesting that the minor components are critical to the synergistic activity. The essential oils of the wild populations of A. mendozana, were examined by GC/MS, and their chemical compositions were compared. Moreover, antibacterial activity was determined by the microdilution technique according to CLSI, using reference and clinical isolate strain of E. coli. The chemical composition was similar for all populations of A. mendozana, in different ratios. The main compounds were Camphene, Alpha-thujone and Camphor and the minor constituents: artemiseole and artemisia alcohol. The antibacterial analysis showed that all oils presented an interesting activity against E. coli ATCC and clinical isolate (value MIC of 1500 and 2000 µg/ml). These results are support the use of Essential oils due that its main components have been widely recognized as bactericide compounds. Acknowledgements: Financial support was provided by CICITCA ( I-1011), CONICET (LB, H.M and ZJA)