Influence of acquisition parameters on morphometric values obtained from structural Magnetic Resonance Images

GALIMBERTI, CLARA; RODRIGUEZ MUSSO, A.; EVANGELISTA, IGNACIO; GOMEZ, JUAN CARLOS; PASCARIELLO, GUIDO; DONNELLY-KEHOE, PATRICIO ANDRES

Viena

Congreso; European Congress of Radiology; 2019

European Society of Radiology

Structural MRI (sMRI) of the brain in the clinical environment usually consist in a qualitative analysis, in which the neuroradiologist detects deviations or anomalies by visual inspection. A quantitative analysis can complement the specialist´s opinion, allowing a comparative study among subjects. However, to perform a reliable analysis, it is necessary to consider each measure´s distribution in the healthy population. In thiswork we used a large sample from several public databases to study the influence of acquisition parameters on the measurement of neuromorphometric features computed with Freesurfer. Then, we applied them to study Alzheimer´s disease (AD) and Mild Cognitive Impairment (MCI) from a machine learning perspective.