INVESTIGADORES
TOLOZA Ariel Ceferino
congresos y reuniones científicas
Título:
COMPARATIVE TOXICITY OF OXYGENATED MONOTERPENOIDS IN EXPERIMENTAL HYDRO-ALCOHOLIC LOTIONS: CORRELATION WITH PHYSICAL PARAMETERS
Autor/es:
GONZALEZ AUDINO P, MOUGABURE CUETO G, VASSENA C, TOLOZA AC, GALLARDO A, PICOLLO MI
Reunión:
Conferencia; Fourth International Conference on Phthiraptera (ICP4); 2010
Institución organizadora:
National Journal of Turkish Society for Parasitology
Resumen:
The use of
botanical compounds such as essential oils has recently become of great
interest as a natural mean of pest control because of its repellent, ovicidal,
adulticidal and feeding inhibition activity against various insect species
including head lice. Essential oils are the steam-distillable fraction of plant
tissues which are often responsible for a plants distinctive scent, odour or
taste. These oils are of rather complex composition, generally consisting of
low molecular weight monoterpenes and related phenols. Due to the variability
of their constitution the effects may not be reliable, safe and reproducible.
Thus, it was our objective to test and compare the efficacy of pure oxygenated
monoterpenoids which are main ingredients of essential oils that have proved
good biological activity. We used pulegon and citral, components of Aloysia
citrodora, and geraniol, citronelol, eugenol, mentol and linalool, components
of geranium oil. The toxic activities were evaluated by the immersion method of
head lice in hidro-alcoholic solutions. We tested ethanolic solutions from 0 to
70% and monoterpenoid concentrations from 0.05 to 10%. As end point we
evaluated both inactivation and mortality of head lice. We found that
citronelol and geraniol showed the highest mortality (>60%). Pulegone,
linalool, mentol and citral produced inactivation between 42 and 55%, and
mortality between 34 and 53%. A simple linear regression analyses showed
statistically significant relationships between the toxic effects and viscosity
of the monoterpenoids (p<0.05) but no with their log P.
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