THE ROLE OF BASAL BIOCHEMICAL TESTS IN THE DIAGNOSTIC WORK-OUT OF GROWTH HORMONE DEFICIENCY (GHD) IN THE NEWBORN PERIOD.

BALLERINI MG; BRASLAVSKY D; GOTTA G; RODRIGUEZ ME; KESELMAN A; ROPELATO MG; BERGADÁ I

Washington

Congreso; 10th International Meeting of Pediatric Endocrinology; 2017

Objectives: GHD diagnosis represents a challenge in neonates in whom provocative tests are difficult to implement. The accuracy of basal GH-IGFs biomarkers in the diagnostic work-out of GHD in neonates is still controversial.To assess the diagnostic accuracy of basal GH/IGF-I/IGFBP3 concentrations for GHD diagnosis and to evaluate serum GH usefulness under hypoglycemia in neonates.Methods: Retrospective case-control study of 25 full-term neonates [median age (m): 25 days] with confirmed GHD based on growth retardation, stimulated GH