INVESTIGADORES
PICOLLO Maria Ines
congresos y reuniones científicas
Título:
Comparative toxicity of oxygenated monoterpenoids in experimental hydro-alcoholic lotions. Correlation with physical parameters
Autor/es:
PAOLA GONZÁLEZ AUDINO, C. VASSENA, G. MOUGABURE CUETO, A. TOLOZA, A. GALLARDO & M.I. PICOLLO
Lugar:
Urgup, Cappadocia
Reunión:
Congreso; 9. Fourth International Conference on Phthiraptera (ICP4); 2010
Institución organizadora:
International Society of Phthirapterists
Resumen:
The use of botanical
compounds such as essential oils has recently become of great interest as a natural mean of
pest control because of its repellent, ovicidal, adulticidal and feeding
inhibition activity against various insect species including head lice.
Essential oils are the steam-distillable fraction of plant tissues which are
often responsible for a plants distinctive scent, odour or taste. These oils
are of rather complex composition, generally consisting of low molecular weight
monoterpenes and related phenols. Due to the variability of their constitution
the effects may not be reliable, safe and reproducible.
Thus, it was our objective to test and compare the efficacy of pure oxygenated
monoterpenoids which are main ingredients of essential oils that have proved
good biological activity. We used pulegon
and citral, components of Aloysia
citrodora, and geraniol, citronelol, eugenol, mentol and linalool,
components of geranium oil.
The toxic
activities were evaluated by the immersion method of head lice in hidro-alcoholic
solutions. We tested ethanolic solutions from 0 to 70% and monoterpenoid
concentrations from 0.05 to 10%. As end point we evaluated both inactivation
and mortality of head lice. We found that citronelol and geraniol showed the
highest mortality (>60%). Pulegone, linalool, mentol and citral produced inactivation
between 42 and 55%, and mortality between 34 and 53%.
A simple
linear regression analyses showed statistically significant relationships
between the toxic effects and viscosity of the monoterpenoids (p<0.05) but
no with their log P.