OmpQ, a Bvg-regulated outer membrane protein involved in Bordetella bronschiseptica biofilm formation

ARNAL, LAURA; YANTORNO, OSVALDO; VILLALBA, MARÍA INÉS; SERRA, DIEGO OMAR; CATTELÁN, NATALIA; PARISI, GUSTAVO

Buenos Aires

Simposio; 11th International Bordetella Symposium; 2016

Comité Internacional de Bordetella

Bordetella bronchiseptica has the ability of living in sessile communities, known as biofilms, on abiotic surfaces and in the respiratory tract of mice (1-3). OmpQ is a general outer membrane porin of Bordetella, whose expression is regulated by the two-component system BvgAS, together with other virulence factors of these bacteria (4). We have previously found an over expression of this protein in biofilms from B. pertussis (5). The purpose of this work was to study the contribution of OmpQ to biofilm formation by B. bronchiseptica. References1- Mishra, M., et al. J Bacteriol, 2005. 2- Sloan, G.P., et al. J Bacteriol, 2007. 3- Serra, D.O., et al. PLoS ONE, 2012. 4- Finn, T.M., et al. J Bacteriol, 1995. 5- Arnal, L., et al. Front Microbiol, 2015.