GLP-1, GLYCAEMIA, INSULINEMIA AND HOMA THROUGH ORAL GLUCOSE TOLERANCE TEST IN DOGS WITH CUSHING'S SYNDROME

MICELI, DD; CABRERA BLATTER, MF; CASTILLO, VA; PIGNATARO, OP

Chascomús

Jornada; XV JORNADAS ANUALES DE LA SOCIEDAD ARGENTINA DE BIOLOGÍA; 2013

SAB

Objectives: The aim of this study was to assess GLP-1, glucose and insulin concentrations, HOMAβ-cell function andHOMAinsulinsensitivity in dogs with Cushing's Syndrome (CS), and compare these values with those in normal and obese dogs.Methods: Three groups were formed (n=6 each group): CS-group, Obese-group and Control-group. They performed the OralGlucose Tolerance Test (OGTT) to dose GLP-1, glycaemia and insulin levels while baseline, 15, 30, 60 and 120 minutes (m).Statistical analysis was performed using ANOVA Friedman test followed by Dunn's multiple-comparison. Values areexpressed as median and interquartile ranges (P