ANTIBACTERIAL ACTIVITY OF PROPOLIS FROM NEUQUEN, ARGENTINA

VILLOLDO, N.C.; SAMPIETRO, D.A.; VATTUONE, M.A.

Tafi del Valle

Congreso; XXVIII Annual scientific meeting of the Tucuman biology association; 2011

Tucuman biology association

Introduction: Propolis, which is produced by bees, is used to prevent bacterial and fungal infections in the hive. It is widely used in folk medicine because it conta ins high levels of bioactive compounds. Aim: To determine the antibacterial activity of ethanolic extracts of partially purified propolis (EPPP) from different areas of Neuquen, Argentina (Centro B, Note A and Confluencia). Methods: The susceptibility testing was performed using macrodilution assays. Dilutions of EPPP were mixed with Mueller Hinton agar medium in Petri dishes. Bacterial strains of Collection ATCC and local bacterial isolates (lEV) were used. Results and Conclusions: All extracts inh ibited the growth of the tested strains. Centro B extract had the lowest minimum inhibitory concentration (MIC) for E. coli ATCC 25922 and P. aerug inosa ATCC 27853 (11.77 µg/ ml). Confluencia extract had the lowest MIC for E. coli IEV30 (12.2 1 µg / ml) and Norte A extract was more bioactive against P. aeruginosa ATCC 27853 (MIC: 8.80 ug / ml). The highest MIC value was observed for S aureus ATCC 292 13. These are promising result s suggesting that these extracts could be used to tre at bacterial infections.