Case report of transient neonatal diabetes in a foal.

FREZZA, MARIEL; KEHOE, PATRICIO; TUEMMERS, CHRISTIAN; MURIEL, MARCOS

Congreso; 17º Congreso WEVA 2023; 2023

INTRODUCTIONTransient neonatal diabetes mellitus (TNDM) is described in human medicine but reports in equine medicine are scarce. The objective of this work is to describe a case of transient neonatal diabetes in a foal.CLINICAL HISTORYMale foal, small crossbreed, 15 kg, 12 days old. History of weakness and restricted intrauterine growth at birth as a consequence of fetal stress (mother with very low body condition and severe injuries), treated with antibiotic therapy and plasma transfusion. The hematology and blood biochemistry (including glycemia) at 12 hours after birth yielded results within normal values.RELEVANT CLINICAL FINDINGSThe patient presented weakness and depression with response to stimuli, mild hyperthermia, dehydration, weak metatarsal pulse, hyperglycemia, white colored serum and the owner commented that the stools were also whitish.EVIDENCE-BASED DIAGNOSISHematology and blood biochemistry showed leukopenia with a left shift, a slight increase in total protein and fibrinogen, an increase in urea, a marked increase in triglycerides, and low levels of pancreatic enzymes (amylase 2 U/l), lipase 13 IU/l). Cortisol measured 1.9 μg/dl and insulin