INVESTIGADORES
FERRER Evelina Gloria
congresos y reuniones científicas
Título:
Improvement of the cardiovascular effect of methyldopa by complexation with Zn(II): synthesis, characterization and mechanism of action
Autor/es:
ACTIS DATO, A.; MARTÍNEZ, VALERIA R.; VELEZ RUEDA, JORGE O.; PORTIANSKI E.; DE GIUSTI, VERÓNICA; FERRER E.G.; WILLIAMS P.A.M.
Lugar:
Puerto Varas
Reunión:
Congreso; PANAM Physiological Sciences 2023; 2023
Institución organizadora:
Sociedad Chilena de Ciencias Fisiológicas (SCHCF) and Asociación Latinoamericana de Ciencias Fisiológicas (ALACF)
Resumen:
Introduction: α-methyldopa (MD) is used for managing hypertension during pregnancy. Zinc deprivation has been associated with many diseases.Objectives: The synthesis of a Zn coordination complex [Zn(MD)(OH)(H2O)2].H2O (ZnMD) provide a promising alternative pathway to improve the biological properties of MD.