Analysis of transformations of oxytetracycline in water/sediment systems by HPLC-MSn

FEDERICO M. IVANIC; ROBERTO J. CANDAL; MATIAS BUTLER

Rio de Janeiro

Congreso; III IBEROAMERICAN Conference on Mass Spectrometry; 2023

Sociedade Brasileira de Espectrometria de Massas

I Oxytetracycline (OTC) is a broad-spectrum antibiotic that, due to its intensive use in livestock, may be regarded as emerging contaminant (EC). As other ECs, OTC may degrade in the environment, generating transformation products (TPs), which could potentially be more harmful than their parent compound. Laboratory experiments allow to simulate diverse environmental conditions and characterize multiple TPs of low abundance through HPLC-MSn. Batch simulated degradation experiments have proven to be useful to examine the fate of OTC in water/sediment systems under different conditions. HPLC-MSn and extensive ion fragment analysis allowed to characterize several TPs and to assess their persistence in solution and sediments.