INVESTIGADORES
PIDRE Matias Luis
congresos y reuniones científicas
Título:
MITOCHONDRIAL PEPTIDE HUMANIN (HN) ENHANCES CHEMORESISTANCE OF GLIOBLASTOMA CELLS
Autor/es:
ZUCCATO CAMILA; ASAD ANTONELA; NICOLA CANDIA ALEJANDRO JAVIER; SAGRIPANTI SOFÍA; ABT ARACELI A.; PIDRE MATIAS LUIS; ROMANOWSKI VÍCTOR; SEILICOVICH ADRIANA; CANDOLFI MARIANELA
Lugar:
Mar del Plata
Reunión:
Congreso; LXIII Reunión Anual de la Sociedad Argentina de Investigación Cínica (SAIC); 2018
Institución organizadora:
SAIC
Resumen:
Humanin (HN) is a mitochondrial-derivedpeptidewithpotentcytoprotective effect in many celltypes. Administration of HN hasbeen proposed as a therapeuticapproach for several chronicdiseases. Although HN has beenshown to protect normal tissuesagainst the toxic effects ofchemotherapy, its role in tumorchemoresistanceispoorlyunderstood. We aimed to evaluatewhether HN affects the sensitivityof GBM cells to chemotherapy.
