Development of polyesterurethane scaffolds by 3D printing for tissue engineering

LORES, NAYLA J.; HUNG HUNG, YUK MING X.; TALOU, MARIANO H.; ABRAHAM, GUSTAVO A.; CARACCIOLO, PABLO C.

Mar del Plata

Simposio; XVI Simposio Latinoamericano de Polímeros - SLAP 2018; 2018

Instituto de Investigaciones en Ciencia y Tecnología de Materiales (INTEMA, CONICET - UNMDP)

In recent years 3D printing technologies have gained the attention of researchers specialized in tissue engineering (TE). The mean role of 3D printing in TE is to provide a microenvironment that mimics the intricate properties of the native extracellular matrix (ECM), favoring the infiltration of seeded cells and conducting to the generation of a specific tissue. Moreover, 3D printing technology must be able to yield quality scaffolds with controlled pore size, interconnectivity, adequate mechanical strength, biodegradability, and the ability to support cellular growth. For all these reasons, the aim of this work is to fabricate bioresorbable scaffolds by fused deposition modelling (FDM) using filaments obtained by extrusion of segmented polyesterurethanes (SPU). 3D printed scaffolds based on SPU were fabricated successfully. The printed structures showed dimensional stability and high reproducibility. The desired geometry, pore size and porosity could be achieved by setting FDM parameters.