Efecto del octilfenol sobre la síntesis de vitelogenina y la morfología gonadal en el pez cíclido Cichlasoma dimerus (Telesotei, Perciformes).

REY VÁZQUEZ, G.; DA CUÑA, R.; PIAZZA, Y.; MEIJIDE, F.; LO NOSTRO, F.; BABAY, P.; TRUDEAU,V.; MAGGESE, C.; GUERRERO, G.

Química y Toxicología Ambiental en América Latina.

SETAC PRESS

Lugar: Buenos Aires; Año: 2009; p. 179 - 181

Exposure to environmental pollutants may disrupt endocrine functions and cause reproductive effects in human and wildlife populations. Various groups of chemicals have estrogen-like effects, including the degradation products of alkylphenolpolyethoxylates, such as octylphenol (OP). In this study, the effect of OP on the cichlid fish Cichlasoma dimerus was evaluated using changes in the levels of vitellogenin (VTG) in plasma and surface mucus, and histological alterations in the gonads as endpoints. Adult males and females were exposed to 30, 150 and 300 mg/l OP under semistatic conditions, during 60 days. Blood and surface mucus samples were taken at the end of the experiment and heterologous antisera were used in Dot and Western blot techniques. VTG was detected in plasma and mucus of control and treated females, as well as in samples from treated males. Impairment of gonadal structure was evidenced in males from 150 and 300 mg/l OP. The most salient pathological change in testicular architecture was an increased testicular fibrosis. Furthermore, abnormality of spermatogenesis was observed in fish from 300 mg/l OP.