Cardiac interoception in neurological conditions and its relevance for dimensional approaches.

ADRIÁN YORIS; ADOLFO M. GARCÍA; PAULA SALAMONE; LUCAS SEDEÑO; INDIRA GARCÍA-CORDERO; AGUSTÍN IBÁÑEZ

The Interoceptive Basis of the Mind

Oxford University Press

Lugar: Oxford; Año: 2018; p. 225 - 234

Dimensional and transdiagnostic approaches have revealed multiple cognitive and emotional alterations shared by several neuropsychiatric conditions. While this has been shown for externally triggered neurocognitive processes, the disruption of interoception across brain disorders remains poorly understood. This chapter aims to fill this gap while proposing cardiac interoception as a potential common biomarker across neurological. It focuses on key aspects of cardiac interoception, such as the mechanisms underlying different interoceptive dimensions; the relationship among interoception, emotion, and social cognition; and the roles of different interoceptive pathways. It considers behavioral, neuroanatomical, and brain functional evidence, and discusses available findings in the context of an experimental and clinical agenda to evaluate the potential role of interoception as a predictor of clinical outcomes, a marker of neurocognitive deficits in neurological diseases, and a general source of insights for breakthroughs in the treatment and prevention of multiple disorders. Finally, future directions to improve the dimensional and transdiagnostic assessment of interoception in multiple pathologies are outlined.