Neurobiology of Circadian and Interval Timing

AGOSTINO P.V.; ACOSTA J.; MECK W.H.

Encyclopedia of Life Sciences

John Wiley & Sons Ltd

Lugar: Chichester; Año: 2017; p. 1 - 11

Temporal processing in the brain ranges from microsecond to seasonal frequencies. Two of the main scales of biological timing ubiquitous in most organisms are interval timing (seconds-to-minute range) and circadian timing (24 hours range). Several brain areas, circuits and neuromodulators that are critical to temporal processing have been now identified. However, with the exception of the circadian system, the genetic and molecular machinery that regulates biological clocks has not been systematically examined. As a consequence, the molecular basis of these two temporal mechanisms is currently the subject of intense research, as well as their possible relationship.