Starches in drug delivery

GARCIA, NANCY LIS; FASCIO, MIRTA L.; D'ACCORSO, NORMA

Natural Biopolymers for drug delivery

ELSEVIER

Año: 2024; p. 324 - 376

In the last few years, the use of materials from renewable biomass in drug delivery has received g considerable attention. Starch is an abundant, eco-friendly, biodegradable polysaccharide with great possibility of being scaled to an industrial level. Because starch can be physically processed by various methodologies, such as annealing, dry heating, heat-moisture and ultrasonic treatment resulting in a very interesting versatility in scaling processes. Moreover, the starch derivatives result in versatile derivatives that are capable of interacting with different drugs. In this sense, starch can be hydrolyzed, esterified, grafted, oxidized which allows it to be used in different biological applications. In this chapter summarizes the last relevance advances with starch, such as microspheres, hydrogels, nanocrystals, films, nanoparticles and their uses such as transdermal drug delivery, release of anticancer drugs, antibacterial hydrogel, colon diseases and their potential applications as drug delivery.