INVESTIGADORES
BRUMOVSKY Pablo Rodolfo
artículos
CASADEI, MAILIN; MIGUEL, BERNARDO; RUBIONE, JULIA; FIORE, ESTEBAN; MENGELLE, DIEGO; GUERRI-GUTTENBERG, ROBERTO; MONTANER, ALEJANDRO; VILLAR, MARCELO J.; CONSTANDIL, LUIS; ROMERO-SANDOVAL, E ALFONSO; BRUMOVSKY, PABLO
Mesenchymal Stem Cell Engagement Modulates Neuroma Microenviroment in Rats and Humans and Prevents Postamputation Pain
Journal of Pain; Año: 2024
RUBIONE, JULIA; SBRASCINI, SANDRA; MIGUEL, BERNARDO; LEIGUARDA, CANDELARIA; CORONEL, MARÍA FLORENCIA; MCCARTHY, CARLY J.; MONTANER, ALEJANDRO DANIEL; VILLAR, MARCELO JOSÉ; BRUMOVSKY, PABLO RODOLFO
Modulation of the inflammatory response by pre-emptive administration of IMT504 reduces postoperative pain in rats and has opioid-sparing effects
JOURNAL OF PAIN; Lugar: ESCOCIA; Año: 2023
BRUMOVSKY, PABLO R.; ASLA, MARIANO; VILLAR, MARCELO J.
Chronic pain: try new routes to more tailored treatments
NATURE; Año: 2023 vol. 617
NOYA-RIOBÓ, MARÍA VICTORIA; MIGUEL, CONSTANZA ÁGATA; SORIANO, DELIA BEATRIZ; BRUMOVSKY, PABLO RODOLFO; VILLAR, MARCELO JOSÉ; CORONEL, MARÍA FLORENCIA
Changes in the expression of endocannabinoid system components in an experimental model of chemotherapy-induced peripheral neuropathic pain: Evaluation of sex-related differences
EXPERIMENTAL NEUROLOGY; Año: 2023 vol. 359
ATMANI, KARIM; MELEINE, MATHIEU; LANGLOIS, LUDOVIC; COËFFIER, MOÏSE; BRUMOVSKY, PABLO; LEROI, ANNE-MARIE; GOURCEROL, GUILLAUME
Involvement of acid sensing ion channel (ASIC)-3 in an acute urinary bladder-colon cross sensitization model in rodent
Frontiers in Pain Research; Año: 2023 vol. 4
CASADEI, MAILÍN; FIORE, ESTEBAN; RUBIONE, JULIA; DOMÍNGUEZ, LUCIANA MARÍA; CORONEL, MARÍA FLORENCIA; LEIGUARDA, CANDELARIA; GARCÍA, MARIANA; MAZZOLINI, GUILLERMO; VILLAR, MARCELO J.; MONTANER, ALEJANDRO; CONSTANDIL, LUIS; ROMERO-SANDOVAL, E ALFONSO; BRUMOVSKY, PABLO R.
IMT504 blocks allodynia in rats with spared nerve injury by promoting the migration of mesenchymal stem cells and by favoring an anti-inflammatory milieu at the injured nerve
Pain; Año: 2022 vol. 163 p. 1114 - 1129
MIGUEL, CONSTANZA ÁGATA; NOYA-RIOBÓ, MARÍA VICTORIA; BRUMOVSKY, PABLO RODOLFO; VILLAR, MARCELO JOSÉ; CORONEL, MARÍA FLORENCIA
Sex-related differences in oxaliplatin-induced changes in the expression of transient receptor potential channels and their contribution to cold hypersensitivity
NEUROSCIENCE LETTERS; Año: 2022 vol. 788
RIOS, ANTONELLA S.; DE VINCENTI, ANA PAULA; CASADEI, MAILIN; AQUINO, JORGE B.; BRUMOVSKY, PABLO R.; PARATCHA, GUSTAVO; LEDDA, FERNANDA
Etv4 regulates nociception by controlling peptidergic sensory neuron development and peripheral tissue innervation
DEVELOPMENT; Año: 2022 vol. 149
LEIGUARDA, C.; VILLARREAL, A.; POTILINSKI, C.; PELISSIER, T.; CORONEL, M.F.; BAYO, J.; RAMOS, A.J.; MONTANER, A.; VILLAR, M.J.; CONSTANDIL, L.; BRUMOVSKY, PABLO R.
Intrathecal Administration of an Anti‐nociceptive Non-CpG Oligodeoxynucleotide Reduces Glial Activation and Central Sensitization
JOURNAL OF NEUROIMMUNE PHARMACOLOGY; Año: 2021
GUO, TIANTIAN; PATEL, SHIVAM P; SHAH, DHRUV; CHI, LING; EMADI, SHARAREH; PIERCE, DAVID M; HAN, MARTIN; BRUMOVSKY, PABLO RODOLFO; FENG, BIN
Optical clearing reveals TNBS-induced morphological changes of VGLUT2-positive nerve fibers in mouse colorectum
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY; Año: 2021
LEIGUARDA, CANDELARIA; POTILINSKI, CONSTANZA; RUBIONE, JULIA; TATE, PABLO; VILLAR, MARCELO J.; MONTANER, ALEJANDRO; BISAGNO, VERÓNICA; CONSTANDIL, LUIS; BRUMOVSKY, PABLO R.
IMT504 Provides Analgesia by Modulating Cell Infiltrate and Inflammatory Milieu in a Chronic Pain Model
JOURNAL OF NEUROIMMUNE PHARMACOLOGY; Año: 2021
LEIGUARDA, CANDELARIA; MCCARTHY, CARLY J.; CASADEI, MAILIN; LUNDGREN, KERSTIN H.; CORONEL, MARÍA FLORENCIA; TRIGOSSO-VENARIO, HARRY; SEAL, REBECCA P.; SEROOGY, KIM B.; BRUMOVSKY, PABLO R.
Transcript Expression of Vesicular Glutamate Transporters in Rat Dorsal Root Ganglion and Spinal Cord Neurons: Impact of Spinal Blockade during Hindpaw Inflammation
ACS Chemical Neuroscience; Año: 2020
LEIGUARDA, CANDELARIA; CORONEL, MARÍA FLORENCIA; MONTANER, ALEJANDRO DANIEL; VILLAR, MARCELO JOSÉ; BRUMOVSKY, PABLO RODOLFO
Long-lasting ameliorating effects of the oligodeoxynucleotide IMT504 on mechanical allodynia and hindpaw edema in rats with chronic hindpaw inflammation
NEUROSCIENCE LETTERS; Año: 2018 vol. 666 p. 17 - 23
USACH, V.; CORONEL, MARÍA FLORENCIA; MALET, MARIANA; PIÑERO, GONZALO; LEIGUARDA, CANDELARIA; CASADEI, MAILIN; VILLAR, MARCELO JOSÉ; SETTON, P.; BRUMOVSKY, PABLO RODOLFO
Bone Marrow-Derived Cells and Peripheral Nerve Injury: Translational Implications for Pain and Regeneration Treatments
Clinical Pharmacology and Translational Medicine; Lugar: Scottsdale, Arizona; Año: 2018 vol. 2 p. 112 - 124
CORONEL MF; VILLAR MJ; BRUMOVSKY, PR; GONZALEZ, S
Spinal Neuropeptide Expression and neuropathic behaviour in the acute and chronic phases after spinal cord injury: Effects of progesterone administration
PEPTIDES; Lugar: Amsterdam; Año: 2017 vol. 88 p. 189 - 195
MALET, MARIANA; LEIGUARDA, CANDELARIA; GASTÓN, GUILLERMO; MCCARTHY, CARLY; BRUMOVSKY, PABLO
Spinal activation of the NPY Y1 receptor reduces mechanical and cold allodynia in rats with chronic constriction injury
PEPTIDES; Año: 2017
USACH, V.; MALET, MARIANA; LOPEZ TECH, M.; LAVALLE, L.; PIÑERO BIOCHEM, G.; SACCOLITI, M.; CUETO, A.; BRUMOVSKY, PR; BRUSCO, A.; SETTON, P.
Systemic transplantation of bone marrow mononuclear cells promotes axonal regeneration and analgesia in a model of Wallerian degeneration
TRANSPLANTATION; Lugar: Philadelphia; Año: 2017
BRUMOVSKY PR
Dorsal root ganglion neurons and tyrosine hydroxylase ? An intriguing association with implication for sensation and pain
PAIN; Lugar: Amsterdam; Año: 2016 vol. 157 p. 314 - 320
MCCARTHY CJ; TOMASELLA, EUGENIA; MALET, MARIANA; SEROOGY KB; HÖKFELT T; VILLAR MJ; GEBHART GF; BRUMOVSKY, PR
Axotomy of tributaries of the pelvic and pudendal nerves induces changes in the neurochemistry of mouse dorsal root ganglion neurons and the spinal cord
BRAIN STRUCTURE & FUNCTION; Lugar: HEIDELBERG; Año: 2016 vol. 221 p. 1985 - 2004
MALET, MARIANA; BRUMOVSKY PR
VGLUTs and Glutamate Synthesis-Focus on DRG neurons and Pain
Biomolecules; Lugar: Basel; Año: 2015 vol. 5 p. 3416 - 3437
BRUMOVSKY PR; LA JH; GEBHART GF
Distribution across tissue layers of extrinsic nerves innervating the mouse colorectum - an in vitro anterograde tracing study
NEUROGASTROENTEROLOGY AND MOTILITY; Lugar: Londres; Año: 2014 vol. 26 p. 1494 - 1507
BRUMOVSKY PR; SEAL RP; LUNDGREN KH; SEROOGY KB; WATANABE M; GEBHART GF
Expression of vesicular glutamate transporters in sensory and autonomic neurons innervating the mouse urinary bladder
JOURNAL OF UROLOGY; Lugar: Amsterdam; Año: 2013 p. 1 - 32
MALET, MARIANA; VIEYTES, CAROLINA; LUNDGREN KH; SEAL, REBECCA; TOMASELLA, EUGENIA; SEROOGY KB; HÖKFELT T; GEBHART GF; BRUMOVSKY PR
Transcript expression of vesicular glutamate transporters in lumbar dorsal root ganglia and the spinal cord of mice - Effects of peripheral axotomy or hindpaw inflammation
NEUROSCIENCE; Lugar: Amsterdam; Año: 2013 vol. 248 p. 95 - 111
BRUMOVSKY PR
VGLUTs in Peripheral Neurons and the Spinal Cord: Time for a Review.
ISRN Neurology; Año: 2013 vol. 2013 p. 1 - 28
LA JH; FENG B; SCHWARTZ E; BRUMOVSKY PR; GEBHART GF
Luminal hypertonicity and acidity modulate colorectal afferents and induce persistent visceral hypersensitivity
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY; Lugar: Bethesda; Año: 2012 vol. 303 p. 802 - 809
BRUMOVSKY, PR; LA JH; MCCARTHY CJ; HÖKFELT T; GEBHART GF
Dorsal root ganglion neurons innervating pelvic organs in the mouse express tyrosine hydroxylase
NEUROSCIENCE; Lugar: Amsterdam; Año: 2012 vol. 223 p. 77 - 91
BRUMOVSKY PR; SEROOGY KB; LUNDGREN KH; WATANABE M; HÖKFELT T; GEBHART GF
Some lumbar sympathetic neurons develop a glutamatergic phenotype after peripheral axotomy with a note on VGLUT(2)-positive perineuronal baskets
EXPERIMENTAL NEUROLOGY; Año: 2011 p. 1 - 15
BRUMOVSKY PR; ROBINSON DR; LA JH; SEROOGY KB; LUNDGREN KH; ALBERS KM; KIYATKIN ME; SEAL RP; EDWARDS RH; WATANABE M; HÖKFELT T; GEBHART GF
Expression of vesicular glutamate transporters type 1 and 2 in sensory and autonomic neurons innervating the mouse colorectum
JOURNAL OF COMPARATIVE NEUROLOGY; Año: 2011 vol. 519 p. 3346 - 3366
BRUMOVSKY, PR; GONZALEZ, S; VIVÉ, J; MARCHEVSKY, E
Dolor Neuropático ? Parte I. Actualización de su definición, mecanismos y diagnóstico
Neurotarget; Lugar: Buenos Aires; Año: 2011 vol. 6 p. 21 - 28
BRUMOVSKY PR, GEBHART GF.
Visceral organ cross-sensitization - An integrated perspective.
Autonomic Neuroscience; Año: 2010 p. 106 - 115
FENG B, BRUMOVSKY PR, GEBHART GF.
Differential roles of stretch-sensitive pelvic nerve afferents innervating mouse distal colon and rectum
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY; Año: 2010 vol. 298 p. 402 - 409
MCCARTHY CJ, ZABBAROVA IV, BRUMOVSKY PR, ROPPOLO JR, GEBHART GF, KANAI AJ.
Spontaneous contractions evoke afferent nerve firing in mouse bladders with detrusor overactivity.
JOURNAL OF UROLOGY; Año: 2009 vol. 181 p. 1459 - 1466
CORONEL MF, MUSOLINO PL, BRUMOVSKY PR, HÖKFELT T, VILLAR MJ.
Bone marrow stromal cells attenuate injury-induced changes in galanin, NPY and NPY Y1-receptor expression after a sciatic nerve constriction.
NEUROPEPTIDES; Año: 2009 vol. 43 p. 125 - 132
BRUMOVSKY PR, FENG B, XU L, MCCARTHY CJ, GEBHART GF.
Cystitis increases colorectal afferent sensitivity in the mouse.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY; Año: 2009 vol. 297 p. 1250 - 1258
CORONEL MF, BRUMOVSKY PR, HÖKFELT T, VILLAR MJ.
Differential galanin upregulation in dorsal root ganglia and spinal cord after graded single ligature nerve constriction of the rat sciatic nerve.
Journal of Chemical Neuroanatomy; Año: 2008 vol. 35 p. 94 - 100
BRUMOVSKY P, SHI TS, LANDRY M, VILLAR MJ, HÖKFELT T.
Neuropeptide tyrosine and pain.
Trends in Pharmacological Sciences; Año: 2007 vol. 28 p. 93 - 102
HÖKFELT T, BRUMOVSKY P, SHI T, PEDRAZZINI T, VILLAR M.
NPY and pain as seen from the histochemical side.
Peptides; Año: 2007 vol. 28 p. 365 - 372
BRUMOVSKY P, WATANABE M, HÖKFELT T.
Expression of the vesicular glutamate transporters-1 and -2 in adult mouse dorsal root ganglia and spinal cord and their regulation by nerve injury.
Neuroscience; Año: 2007 vol. 147 p. 469 - 490
BRUMOVSKY P, HOFSTETTER C, OLSON L, OHNING G, VILLAR M, HÖKFELT T.
The neuropeptide tyrosine Y1R is expressed in interneurons and projection neurons in the dorsal horn and area X of the rat spinal cord.
Neuroscience; Año: 2006 vol. 138 p. 1361 - 1376
BRUMOVSKY P, MENNICKEN F, O'DONNELL D, HÖKFELT T.
Differential distribution and regulation of galanin receptors- 1 and -2 in the rat lumbar spinal cord.
Brain Research; Año: 2006 vol. 1085 p. 111 - 120
BRUMOVSKY P, HYGGE-BLAKEMAN K, VILLAR MJ, WATANABE M, WIESENFELD-HALLIN Z, HÖKFELT T.
Phenotyping of sensory and sympathetic ganglion neurons of a galanin-overexpressing mouse--possible implications for pain processing.
Journal of Chemical Neuroanatomy; Año: 2006 vol. 31 p. 243 - 262
BRUMOVSKY P, VILLAR MJ, HÖKFELT T.
Tyrosine hydroxylase is expressed in a subpopulation of small dorsal root ganglion neurons in the adult mouse.
Experimental Neurology; Año: 2006 vol. 200 p. 153 - 165
STANIć D, BRUMOVSKY P, FETISSOV S, SHUSTER S, HERZOG H, HÖKFELT T.
Characterization of neuropeptide Y2 receptor protein expression in the mouse brain. I. Distribution in cell bodies and nerve terminals.
Journal of Comparative Neurology; Año: 2006 vol. 499 p. 357 - 390
HOLMBERG K, KUTEEVA E, BRUMOVSKY P, KAHL U, KARLSTRÖM H, LUCAS GA, RODRIGUEZ J, WESTERBLAD H, HILKE S, THEODORSSON E, BERGE OG, LENDAHL U, BARTFAI T, HÖKFELT T.
Generation and phenotypic characterization of a galanin overexpressing mouse.
Neuroscience; Año: 2005 vol. 133 p. 59 - 77
BRUMOVSKY P, STANIC D, SHUSTER S, HERZOG H, VILLAR M, HÖKFELT T.
Neuropeptide Y2 receptor protein is present in peptidergic and nonpeptidergic primary sensory neurons of the mouse.
Journal of Comparative Neurology; Año: 2005 vol. 489 p. 328 - 348
LANDRY M, LIU HX, SHI TJ, BRUMOVSKY P, NAGY F, HÖKFELT T.
Galaninergic mechanisms at the spinal level: focus on histochemical phenotyping.
Neuropeptides; Año: 2005 vol. 39 p. 223 - 231
BRUMOVSKY PR, BERGMAN E, LIU HX, HÖKFELT T, VILLAR MJ.
Effect of a graded single constriction of the rat sciatic nerve on pain behavior and expression of immunoreactive NPY and NPY Y1 receptor in DRG neurons and spinal cord.
Brain Research; Año: 2004 vol. 1006 p. 87 - 99
HYGGE-BLAKEMAN K, BRUMOVSKY P, HAO JX, XU XJ, HÖKFELT T, CRAWLEY JN, WIESENFELD-HALLIN Z.
Galanin over-expression decreases the development of neuropathic pain-like behaviors in mice after partial sciatic nerve injury.
Brain Research; Año: 2004 vol. 1025 p. 152 - 158
FETISSOV SO, JACOBY AS, BRUMOVSKY PR, SHINE J, IISMAA TP, HÖKFELT T.
Altered hippocampal expression of neuropeptides in seizure-prone GALR1 knockout mice.
Epilepsia; Año: 2003 vol. 44 p. 1022 - 1033
2. BRUMOVSKY PR, SHI TJ, MATSUDA H, KOPP J, VILLAR MJ, HÖKFELT T.
NPY Y1 receptors are present in axonal processes of DRG neurons.
Experimental Neurology; Año: 2002 vol. 174 p. 1 - 10
MATSUDA H, BRUMOVSKY PR, KOPP J, PEDRAZZINI T, HÖKFELT T.
Distribution of neuropeptide Y Y1 receptors in rodent peripheral tissues.
Journal of Comparative Neurology; Año: 2002 vol. 449 p. 390 - 404
1. LIU HX, BRUMOVSKY P, SCHMIDT R, BROWN W, PAYZA K, HODZIC L, POU C, GODBOUT C, HÖKFELT T.
Receptor subtype-specific pronociceptive and analgesic actions of galanin in the spinal cord: selective actions via GalR1 and GalR2 receptors
Proceedings of the National Academy of Sciences; Año: 2001 vol. 98 p. 9960 - 9964