KAUFMAN, TEODORO S; LARGHI, ENRIQUE L.; BRACCA, ANDREA B.J.; SIMONETTI, SEBASTIAN O.

Recent developments in the total synthesis of natural products using the Ugi multicomponent reactions as the key strategy

ORGANIC & BIOMOLECULAR CHEMISTRY; Año: 2024

LARGHI, ENRIQUE L.; BRACCA, ANDREA B. J.; SIMONETTI, SEBASTIAN O.; KAUFMAN, TEODORO S.

Relevant Developments in the Use of Three‐Component Reactions for the Total Synthesis of Natural Products. The last 15 Years

ChemistryOpen; Año: 2024

BOLIVAR ÁVILA, SANTIAGO J.; LEDESMA, GABRIELA N.; KAUFMAN, TEODORO S.; TESTERO, SEBASTIÁN A.; LARGHI, ENRIQUE L.

Step-Economic Total Synthesis of Melosatin A from Eugenol

ACS Omega; Año: 2023

THOBOKHOLT, ELIDA N.; SIMONETTI, SEBASTIÁN O.; KAUFMAN, TEODORO S.; LARGHI, ENRIQUE L.; BRACCA, ANDREA B. J.

Efficient Buchwald–Hartwig and nitrene-mediated five-membered ring closure approaches to the total synthesis of quindoline. Unexpected direct conversion of a nitro group into a phosphazene

RSC Advances; Lugar: LONDRES; Año: 2023 vol. 13 p. 13715 - 13724

FERRETTI, MATÍAS D.; RODRIGUEZ, MARÍA VICTORIA; FERRETTI, ANABELA; NOCITO, ISABEL; BETTUCCI, GABRIEL R.; SREBOT, MARÍA SOL; LARGHI, ENRIQUE L.; MARTÍNEZ, MARÍA LAURA

Antiprotozoal Effect of Baccharis spicata and B. punctulata Volatile Oils and Their Active Components Against Trypanosoma cruzi

Revista Brasileira de Farmacognosia; Año: 2022 vol. 32 p. 133 - 138

LARGHI, ENRIQUE L.; BRUNEAU, ALEXANDRE; SAUVAGE, FÉLIX; ALAMI, MOUAD; VERGNAUD-GAUDUCHON, JULIETTE; MESSAOUDI, SAMIR

Synthesis and Biological Activity of 3-(Heteroaryl)quinolin-2(1H)-ones Bis-Heterocycles as Potential Inhibitors of the Protein Folding Machinery Hsp90

MOLECULES; Año: 2022 vol. 27

VARGAS, DIDIER F.; KAUFMAN, TEODORO S.; LARGHI, ENRIQUE L.

Total Synthesis of Aqabamycin G, a Nitrophenyl Indolylmaleimide Marine Alkaloid from Vibrio sp . WMBA

JOURNAL OF ORGANIC CHEMISTRY; Año: 2022

SIMONETTI, SEBASTIÁN O.; KAUFMAN, TEODORO S.; LARGHI, ENRIQUE L.

Conjugation of Carbohydrates with Quinolines: A Powerful Synthetic Tool

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY; Año: 2022

VARGAS, DIDIER F.; LARGHI, ENRIQUE L.; KAUFMAN, TEODORO S.

Evolution of the Synthesis of Remdesivir. Classical Approaches and Most Recent Advances

ACS Omega; Año: 2021

FERNÁNDEZ, LUCIANA; REVIGLIO, ANA LUCÍA; HEREDIA, DANIEL A.; MORALES, GUSTAVO M.; SANTO, MARISA; OTERO, LUIS; ALUSTIZA, FABRISIO; LIAUDAT, ANA CECILIA; BOSCH, PABLO; LARGHI, ENRIQUE L.; BRACCA, ANDREA B.J.; KAUFMAN, TEODORO S.

Langmuir-Blodgett monolayers holding a wound healing active compound and its effect in cell culture. A model for the study of surface mediated drug delivery systems

Heliyon; Año: 2021 vol. 7

VARGAS, DIDIER F.; ROMERO, BRENDA S.; LARGHI, ENRIQUE L.; KAUFMAN, TEODORO S.

Rhodium(III)-Catalyzed C-H Activation-Based First Total Synthesis of 6- O -Methyl Anciscochine, an Alkaloid Isolated from Ancistrocladus tectorius

SYNTHESIS-STUTTGART; Año: 2020 vol. 52 p. 119 - 126

SELVERO, MARCEL MANKE; LEDESMA, GABRIELA N.; ABRAM, ULRICH; SCHULZ-LANG, ERNESTO; MOREL, ADEMIR FARIAS; LARGHI, ENRIQUE L.

2,2,2-trifluoroethanol-promoted access to symmetrically 3,3-disubstituted quinoline-2,4-diones

JOURNAL OF FLUORINE CHEMISTRY; Año: 2020 vol. 234

THOBOKHOLT, ELIDA N.; LARGHI, ENRIQUE L.; BRACCA, ANDREA B. J.; KAUFMAN, TEODORO S.

Isolation and synthesis of cryptosanguinolentine (isocryptolepine), a naturally-occurring bioactive indoloquinoline alkaloid

RSC Advances; Año: 2020 vol. 10 p. 18978 - 19002

DIDIER F. VARGAS; ENRIQUE L. LARGHI; TEODORO S. KAUFMAN

Concise synthesis of the ABC-ring system of the azafluoranthene, tropoisoquinoline and proaporphine alkaloids. An olefin hydroacylation/ Pomeranz-Fritsch cyclization approach

SYNTHESIS-STUTTGART; Año: 2019 vol. 51 p. 2030 - 2038

AGUILAR, ABEL A. ARROYO; LEDESMA, GABRIELA N.; TIRLONI, BÁRBARA; KAUFMAN, TEODORO S.; LARGHI, ENRIQUE L.

Convergent First Total Synthesis of Melovinone: A Densely Substituted 3-Methoxy-4-quinolone Isolated from Melochia tomentosa L.

SYNTHESIS-STUTTGART; Año: 2019

VARGAS, DIDIER F.; LARGHI, ENRIQUE L.; KAUFMAN, TEODORO S.

First total synthesis of ampullosine, a unique isoquinoline alkaloid isolated from Sepedonium ampullosporum, and of the related permethylampullosine

RSC Advances; Lugar: Londres; Año: 2019 vol. 9 p. 33096 - 33106

VARGAS, DIDIER F.; LARGHI, ENRIQUE L.; KAUFMAN, TEODORO S.

The 6pi-azaelectrocyclization of azatrienes. Synthetic applications in natural products, bioactive heterocycles, and related fields

NATURAL PRODUCT REPORTS; Año: 2019 vol. 36 p. 354 - 401

DIDIER F. VARGAS; ENRIQUE L. LARGHI; TEODORO S. KAUFMAN

Synthesis of polysubstituted 3-methylisoquinolines through the 6-Pi-electron cyclization/elimination of 1-azatrienes derived from 1,1-dimethylhydrazine

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY; Lugar: Weinheim; Año: 2018

MARCELO PEDROSO; ADRIANA Z. GEHN; MATEUS L. STIVANIN; ENRIQUE L. LARGHI; ROBERT A. BURROW; JACKSON A. L. C. RESENDE; UBIRATAN F. DA SILVA; MARCO A. MOSTARDEIRO; IONARA I. DALCOL; ADEMIR F.MOREL

Absolute Configuration of Clemateol

JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY; Lugar: San Pablo; Año: 2018 vol. 29 p. 881 - 887

SANDRA ESTÉBANEZ; CAROLINA LORENTE; TEODORO S. KAUFMAN; ENRIQUE L. LARGHI; ANDRÉS H. THOMAS; MARIANA P. SERRANO

Photophysical and photochemical properties of 3-methylpterin as a new and more stable pterin-type photosensitizer

PHOTOCHEMISTRY AND PHOTOBIOLOGY; Lugar: Londres; Año: 2018 vol. 94 p. 881 - 889

ARROYO AGUILAR, ABEL A.; BOLÍVAR AVILA, SANTIAGO J.; KAUFMAN, TEODORO S.; LARGHI, ENRIQUE L.

Total Synthesis of Waltherione F, a Nonrutaceous 3-Methoxy-4-quinolone, Isolated from Waltheria indica L. F.

ORGANIC LETTERS; Año: 2018 vol. 20 p. 5058 - 5061

JORGELINA L. PERGOMET; ENRIQUE L. LARGHI; TEODORO S. KAUFMAN; ANDREA B. J. BRACCA

First total synthesis of the only known 2-isopropyliden-2H-benzofuran-3-one isolated from V. luetzelburgii.

RSC Advances; Lugar: Londres; Año: 2017 vol. 7 p. 5247 - 5250

MENDEZ, MARIA V.; DANIEL A. HEREDIA; ENRIQUE L. LARGHI; ANDREA B. J. BRACCA; TEODORO S. KAUFMAN

Efficient total synthesis of neocryptolepine and synthetic access to 6-methylquinindoline from a common intermediate.

RSC Advances; Lugar: Londres; Año: 2017 vol. 7 p. 28298 - 28307

DANIEL A. HEREDIA; ENRIQUE L. LARGHI; TEODORO S. KAUFMAN

A straightforward synthesis of 5-methylaaptamine from eugenol, employing a 6π-electrocyclization reaction of a 1-azatriene

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY; Lugar: Weinheim; Año: 2016 p. 1397 - 1404

SEBASTIÁN O. SIMONETTI; ENRIQUE L. LARGHI; TEODORO S. KAUFMAN

Convenient approach to an advanced intermediate toward the naturally occurring, bioactive 6-substituted 5-hydroxy-4-aryl-1H-quinolin-2-ones

ORGANIC & BIOMOLECULAR CHEMISTRY; Lugar: CAMBRIDGE; Año: 2016 vol. 14 p. 2625 - 2636

SEBASTIÁN O. SIMONETTI; ENRIQUE L. LARGHI; TEODORO S. KAUFMAN

The 3,4-dioxygenated 5-hydroxy-4-aryl-quinolin-2(1H)-one alkaloids. Results of 20 years of research, uncovering a new family of natural products

NATURAL PRODUCT REPORTS; Lugar: CAMBRIDGE; Año: 2016 vol. 33 p. 1425 - 1446

ENRIQUE L. LARGHI; ANDREA B. J. BRACCA; ABEL A. ARROYO AGUILAR; DANIEL A. HEREDIA; JORGELINA L. PERGOMET; SEBASTIÁN O. SIMONETTI; TEODORO S. KAUFMAN

Neocryptolepine: A Promising Indoloisoquinoline Alkaloid with Interesting Biological Activity. Evaluation of the Drug and its Most Relevant Analogs.

Current Topics in Medicinal Chemistry; Lugar: Oak Park; Año: 2015 vol. 15 p. 1683 - 1707

SEBASTIÁN O. SIMONETTI; ENRIQUE L. LARGHI; TEODORO S. KAUFMAN

Alternate and Step-Economic Synthesis of the beta-Methylstyrene Chelating Pre-ligand of the Hoveyda-Grubbs II Catalyst

ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL; Lugar: Londres; Año: 2015 vol. 47 p. 227 - 231

MATIAS D. FERRETTI; ALEXANDRE T. NETO; ADEMIR F.MOREL; TEODORO S. KAUFMAN; ENRIQUE L. LARGHI

Synthesis of Symmetrically Substituted 3,3-Dibenzyl-4-hydroxy-3,4-dihydro-1H-quinolin-2-ones, as Novel Quinoline Derivatives with Antibacterial Activity

EUROPEAN JOURNAL OF MEDICAL CHEMISTRY; Lugar: Paris; Año: 2014 vol. 81 p. 253 - 266

SEBASTIÁN O. SIMONETTI; ENRIQUE L. LARGHI; TEODORO S. KAUFMAN

Facile and convenient sequential homobimetallic catalytic approach towards beta-methylstyrenes. A one-pot Stille cross-coupling/isomerization strategy

ORGANIC & BIOMOLECULAR CHEMISTRY; Lugar: CAMBRIDGE; Año: 2014 vol. 12 p. 3735 - 3743

ENRIQUE L. LARGHI; TEODORO S. KAUFMAN

Modulators of Complement Activation: A Patent Review (2008 - 2013)

EXPERT OPINION ON THERAPEUTIC PATENTS; Lugar: London; Año: 2014 vol. 26 p. 665 - 686

ANDREA B. J. BRACCA; DANIEL A. HEREDIA; ENRIQUE L. LARGHI; TEODORO S. KAUFMAN

Neocryptolepine (Cryprotackieine). A Unique Bioactive Natural Product: Isolation, Synthesis and Profile of its Biological Activity

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY; Lugar: Weinheim; Año: 2014 p. 7979 - 8003

SEBASTIÁN O. SIMONETTI; ENRIQUE L. LARGHI; ANDREA B. J. BRACCA; TEODORO S. KAUFMAN

Angular tricyclic benzofurans and related natural products of fungal origin. Isolation, biological activity and synthesis.

NATURAL PRODUCT REPORTS; Lugar: CAMBRIDGE; Año: 2013 vol. 30 p. 941 - 969

SEBASTIÁN O. SIMONETTI; ENRIQUE L. LARGHI; ANDREA B. J. BRACCA; TEODORO S. KAUFMAN

Synthesis of the unique angular tricyclic chromone structure proposed for Aspergillitine, and its relationship with alkaloid TMC-120B

ORGANIC & BIOMOLECULAR CHEMISTRY; Año: 2012 vol. 10 p. 4124 - 4134

LARGHI, E. L.; OPERTO, MARIA A.; TORRES, MIGUEL R.; KAUFMAN, TEODORO S.

Synthesis and classical pathway Complement inhibitory activity of C7-functionalized filifolinol derivatives, inspired in K-76 COOH

EUROPEAN JOURNAL OF MEDICAL CHEMISTRY; Lugar: Paris; Año: 2012 vol. 55 p. 74 - 84

LARGHI, E. L.; KAUFMAN, T. S.

Synthesis of Oxacycles Employing the Oxa-Pictet-Spengler Reaction. Recent Developments and New Prospects

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY; Lugar: Weinheim; Año: 2011 vol. 27 p. 5195 - 5231

ENRIQUE L. LARGHI; TEODORO S. KAUFMAN

Isolation, synthesis and Complement inhibiting activity of the naturally occurring K-76, its analogues and derivatives

ARKIVOC - ONLINE JOURNAL OF ORGANIC CHEMISTRY; Año: 2011 vol. vii p. 49 - 102

LARGHI ENRIQUE L; BOHN, MARIA L.; KAUFMAN, TEODORO S

Aaptamine and related products. Their isolation, chemical syntheses, and biological activity

TETRAHEDRON; Lugar: Amsterdan; Año: 2009 vol. 65 p. 4257 - 4282

LARGHI ENRIQUE L; OPERTO, MARIA A.; TORRES, MIGUEL R.; KAUFMAN, TEODORO S.

New inhibitors of the complement system inspired in K76-COOH. A SAR study of filifolinol derivatives through modifications of the C3' position

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS; Lugar: Amsterdam; Año: 2009 vol. 19 p. 6172 - 6175

SILVEIRA, CLAUDIO C.; LARGHI, ENRIQUE L.; MENDES, SAMUEL R.; BRACCA, ANDREA B.J.; RINALDI, FRANCIELI; KAUFMAN, TEODORO S.

Electrocyclization-Mediated Approach to 2-Methyltriclisine, an Unnatural Analog of the Azafluoranthene Alkaloid Triclisine

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY; Lugar: Weinheim-Alemania; Año: 2009 p. 4637 - 4645

LARGHI ENRIQUE L; OBRIST, BLAISE. V.; KAUFMAN, TEODORO S

A formal total synthesis of the marine alkaloid aaptamine

TETRAHEDRON; Lugar: Amsterdan; Año: 2008 vol. 64 p. 5236 - 5245

LARGHI ENRIQUE L; KAUFMAN, TEODORO S

A combined RCM-Bischler Napieralski strategy towards the synthesis of the carbon skeleton of excentricine and related stephaoxocanes

TETRAHEDRON; Lugar: Amsterdam; Año: 2008 vol. 64 p. 9921 - 9927

LARGHI, ENRIQUE L; KAUFMAN, TEODORO S

Synthesis of N-Methyl-N-formyltyramine, a new beta-phenethylamide derivative isolated from Cyathobasis fruticulosa (Bunge) Aellen

JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY; Lugar: Sao Paulo; Año: 2006 vol. 17 p. 599 - 602

LARGHI, EL; KAUFMAN, TS

The Oxa-Pictet-Spengler Cyclization. Synthesis of Isochromans and Related Pyran-Type Heterocycles

SYNTHESIS-STUTTGART; Lugar: Stuttgart; Año: 2006 vol. - p. 187 - 220

LARGHI, EL; AMONGERO, M; BRACCA, ABJ; KAUFMAN, TS

The intermolecular Pictet-Spengler condensation with chiral carbonyl derivatives in the stereoselective syntheses of optically-active isoquinoline and indole alkaloids

Arkivoc; Lugar: Gainesville, USA; Año: 2005 vol. - p. 98 - 153

MOREL, ADEMIR F; LARGHI, ENRIQUE L; SELVERO, MARCEL M

Mild, Efficient and Selective Silver Carbonate Mediated O-Alkylation of 4-Hydroxy-2-quinolones: Synthesis of 2,4-Dialkoxyquinolines

SYNLETT; Lugar: New York; Año: 2005 vol. - p. 2755 - 2758

MOREL, AF; LARGHI, EL

First totally asymmetric synthesis of (+)-(R)-geibalansine

TETRAHEDRON-ASYMMETRY; Lugar: Amsterdam; Año: 2004 vol. 15 p. 9 - 10

SILVEIRA, CLAUDIO C.; BRAGA, ANTONIO L.; LARGHI, ENRIQUE L.

Synthesis of Thiol, Selenol, and Tellurol Esters by the Reaction of Organochalcogeno Mercurials with Acid Chlorides

ORGANOMETALLICS; Lugar: New York; Año: 1999 vol. 18 p. 5183 - 5186

SILVEIRA, CLAUDIO C.; LARGHI, ENRIQUE L.

Selenium Stabilized Carbenium Ions on Organic Synthesis

JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY; Lugar: Campinas-SP-Brasil; Año: 1998 vol. 9 p. 327 - 340

LARGHI, ENRIQUE L.; KAUFMAN, TEODORO S.

Preparation of N-Benzylsulfonamido-l,2-Dihydroisoquinolines and Their Reaction with Raney Nickel. A Mild, New Synthesis of Isoquinolines

TETRAHEDRON LETTERS; Lugar: Amsterdam; Año: 1997 vol. 38 p. 3159 - 3162