Nutritional recovery with okara diet prevented hypercholesterolemia, hepatic steatosis and glucose intolerance

LEMES, SIMONE FERREIRA; LIMA, FAENA MOURA; DE ALMEIDA, ANA PAULA CARLI; RAMALHO, ALBINA DE FÁTIMA SILVA; DE LIMA REIS, SILVIA REGINA; MICHELOTTO, LETÍCIA FONSECA; AMAYA-FARFÁN, JAYME; CARNEIRO, EVERARDO MAGALHÃES; BOSCHERO, ANTONIO CARLOS; LATORRACA, MÁRCIA QUEIROZ; VELOSO, ROBERTO VILELA

INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION

TAYLOR & FRANCIS LTD

Año: 2014 vol. 65 p. 745 - 753

0963-7486

We assessed the biological value of an okara diet and its effects on the hormonal and metabolic profile of rats submitted to protein restriction during intra-uterine life and lactation and recovered after weaning. Male rats from mothers fed either 17% or 6% protein during pregnancy and lactation were maintained on 17% casein (CC, LC), 17% okara (CO, LO) or 6% casein (LL) diets over 60 d. The nutritional quality of the okara protein was similar to that of casein. The okara diet was effective in the nutritional recovery of rats in growing that were malnourished in early life. Furthermore, the okara diet reversed the hypercholesterolemia and the hepatic steatosis observed in the malnutrition and prevented glucose intolerance in an animal model prone to diabetes mellitus. © 2014 Informa UK Ltd.