IIBBA 05544
INSTITUTO DE INVESTIGACIONES BIOQUIMICAS DE BUENOS AIRES
Unidad Ejecutora - UE
artículos
Título:
Bacterial Infection Disrupts Clock Gene Expression to Attenuate Immune Responses
Autor/es:
HERNANDO, C. ESTEBAN; SOVERNA, ANA FAIGÓN; VÁZQUEZ, MARTÍN; DE LEONE, MARÍA JOSÉ; CARENO, DANIEL A.; BOLOGNA, NICOLÁS G.; YANOVSKY, MARCELO J.; ROMANOWSKI, ANDRÉS; SUN, HEQUAN; SCHNEEBERGER, KORBINIAN; HERNANDO, C. ESTEBAN; SOVERNA, ANA FAIGÓN; VÁZQUEZ, MARTÍN; DE LEONE, MARÍA JOSÉ; CARENO, DANIEL A.; BOLOGNA, NICOLÁS G.; YANOVSKY, MARCELO J.; ROMANOWSKI, ANDRÉS; SUN, HEQUAN; SCHNEEBERGER, KORBINIAN
Revista:
CURRENT BIOLOGY
Editorial:
CELL PRESS
Referencias:
Año: 2020 vol. 30 p. 1740 - 1747
ISSN:
0960-9822
Resumen:
Little is known regarding the mechanisms involved in the clock-immunity crosstalk. de Leone et al. report that the defense mutant eds4 carries a mutation in NUCLEOPORIN205 which affects its circadian function, and that leads to an attenuation of the transcriptional reprogramming in core clock genes that take place soon after a bacterial infection.
