INVESTIGADORES
LABRIOLA Carlos Alberto
artículos
Título:
Immunocytochemical localisation of calreticulin in Trypanosoma cruzi
Autor/es:
THAIS SOUTO-PADRON · CARLOS A. LABRIOLA · WANDERLEY DE SOUZA
Revista:
HISTOCHEMISTRY AND CELL BIOLOGY.
Editorial:
SPRINGER
Referencias:
Lugar: Germany; Año: 2004 vol. 122 p. 563 - 569
ISSN:
0948-6143
Resumen:
Abstract Calreticulin, a Ca2+ chaperone, is found inmany different locations in various eukaryotic cells, includinglumen of the endoplasmic reticulum, the cellsurface, perinuclear areas and cytosolic granules. In thepresent study, a polyclonal antibody against calreticulinwas used for the immunocytochemical localisation of theprotein in Trypanosoma cruzi. Labelling was observed inthe endoplasmic reticulum, Golgi complex, reservosomes,flagellar pocket, cell surface, cytosol, nucleus and kinetoplast.Significant differences in labelling were observedamong the three evolutive forms of the protozoan. Thefunctional role of calreticulin in T. cruzi is discussed.
